Deals


  • An Ipsen site in Wrexham, UK.
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    Courtesy of Ipsen
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    Ipsen, Skyhawk to develop RNA-targeting pills for rare brain diseases

    The deal, which could be worth up to $1.8 billion, is the latest research collaboration involving small molecule drugs that modify RNA. 

    By April 22, 2024
  • A scientific illustration of amyloid plaques and neurons, colored in blue and orange.
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    selvanegra via Getty Images
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    Eisai hunts for next Alzheimer’s drug with new research pact

    A collaboration with BioArctic will focus on a technology designed to more effectively deliver drugs in the brain, following similar efforts by Roche.

    By April 22, 2024
  • Explore the Trendline
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    Brian Tucker / BioPharma Dive
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    Trendline

    Biotech dealmaking

    Acquisitions of biotech companies have picked up in recent quarters, suggesting depressed valuations may be facilitating deal conversations. Read this trendline for a look at the factors impacting M&A. 

    By BioPharma Dive staff
  • A building showing a logo of Teva Pharmaceutical
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    Courtesy of Teva Pharmaceutical
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    Alvotech deal could heighten biosimilar pressure on Humira

    The agreement may help Alvotech capitalize on a recent policy shift by CVS that has driven major market share declines for AbbVie’s blockbuster drug.

    By April 19, 2024
  • An illustration of engineered CAR-T cells attacking a cancer cell.
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    Nemes Laszlo via Getty Images
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    Roche, Adaptimmune part ways on cell therapy research

    The two companies have ended a collaboration that was struck in 2021 and focused on “off-the-shelf” cell therapies for cancer.

    By April 12, 2024
  • NK Cell (Natural Killer Cell) Attacking a Cancer Cell
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    luismmolina via Getty Images
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    Emerging biotech

    Century buys a startup, raises funding in cell therapy expansion

    The biotech is acquiring Clade Therapeutics and its stem cell technology at a discount price, while adding $60 million via a private placement led by Bain Capital.

    By April 11, 2024
  • Vertex CEO Reshma Kewalramani
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    Permission granted by Vertex Pharmaceuticals
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    Vertex to buy kidney disease drugmaker Alpine for $4.9B

    A proposed $4.9 billion buyout of Alpine Immune Sciences would be the largest ever acquisition for Vertex and align with its "toolkit of technologies" approach to dealmaking.

    By Updated April 11, 2024
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    Mario Tama via Getty Images
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    J&J to acquire Shockwave Medical for $13.1B

    The deal comes just over a week after The Wall Street Journal reported the companies were discussing a merger.

    By Ricky Zipp • Updated April 5, 2024
  • A 3D visualization of antibody drug conjugates.
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    Love Employee via Getty Images
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    Genmab buys ProfoundBio for $1.8B, adding to ADC dealmaking flurry

    The buyout continues a surge in M&A for developers of antibody-drug conjugates and gives Genmab a potential competitor to a medicine AbbVie recently purchased in a multibillion-dollar acquisition.  

    By Kristin Jensen • April 3, 2024
  • People walk past the Nasdaq MarketSite on October 12, 2022 in New York City.
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    Michael M. Santiago via Getty Images
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    Acorda files for bankruptcy, reveals asset sale plan

    Stalking horse bidder Merz Therapeutics could get rights to Acorda’s three marketed drugs if its $185 million proposal holds.

    By April 2, 2024
  • Claudia Ulbrich, CEO, Cardior Pharmaceuticals
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    Permission granted by Cardior
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    ‘The heart is back,’ says Cardior CEO, as Novo’s $1B deal boosts field

    Novo Nordisk’s acquisition of Cardior Pharmaceuticals is a bet on new approaches to cardiovascular disease, says Cardior head Claudia Ulbrich.

    By Michael Gibney • March 28, 2024
  • An AbbVie sign is seen on the outside of a building in California.
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    Courtesy of AbbVie
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    AbbVie to buy immune drug developer Landos

    Worth about $138 million upfront, the deal is another example of pharma interest in new drugs for inflammatory conditions like Crohn’s.

    By March 25, 2024
  • A Novo Nordisk sign is seen on the side of a building.
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    hapabapa via Getty Images
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    Novo to acquire heart failure drug in $1B deal for Cardior

    Cardior’s therapy is currently in mid-stage testing and, should the deal close, Novo plans to start another Phase 2 trial.

    By March 25, 2024
  • Thermo Fisher Scientific
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    Courtesy of Thermo Fisher Scientific
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    Thermo Fisher, Bayer partner to develop companion diagnostics

    The companies aim to identify potential patients for Bayer’s precision cancer therapies and increase access to the treatments.

    By Nick Paul Taylor • March 21, 2024
  • Prostate cancer cells, 3D illustration. Prostate cancer awareness image
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    Dr_Microbe via Getty Images
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    AstraZeneca joins radiopharmaceutical deals spree with $2.4B buyout of Fusion

    The deal hands AstraZeneca a prostate cancer drug that’s designed differently than Novartis’ fast-selling Pluvicto and currently in mid-stage testing. 

    By March 19, 2024
  • The East facade of the Capitol Building in Washington DC.
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    dkfielding via Getty Images
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    BIO changes stance, backs bill to limit China’s role in US biotech

    Pressed by lawmakers, the lobbying group is also “taking steps” to end its relationship with WuXi-AppTec, a major contract manufacturer to the biopharmaceutical industry.

    By March 14, 2024
  • Corporate logos are seen outside  on May 15, 2006, in Macclesfield, England.
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    Christopher Furlong via Getty Images
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    AstraZeneca adds another rare disease drug in $800M buyout of startup Amolyt

    The deal gives AstraZeneca a prospect in late-stage testing for parathyroidism and bolsters a rare disease portfolio that mainly consists of drugs from Alexion. 

    By Kristin Jensen • March 14, 2024
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    sudok1 via Getty Images
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    Boehringer, Sosei Heptares team up in schizophrenia drug deal

    Sosei Heptares could receive more than 700 million euros in a deal to develop medicines aimed at the protein GPR52, an emerging drug target in multiple neurological diseases.

    By March 11, 2024
  • A logo of Gilead Sciences
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    Permission granted by Gilead Sciences
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    Gilead bets on ‘trispecifics’ in latest cancer drug deal

    A small partnership with Merus adds to Gilead’s string of cancer dealmaking, which, so far, has not paid off for the large biotech.

    By March 6, 2024
  • A logo of Gilead Sciences
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    Permission granted by Gilead Sciences
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    Abingworth invests in Trodelvy development in deal with Gilead

    One of the investment firm’s startups will work with Gilead to expand the cancer drug’s label under the unusual arrangement, with Abingworth receiving payment if successful.

    By Kristin Jensen • Feb. 29, 2024
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    Spencer Platt via Getty Images
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    NGM to go private through deal with investment firm

    The deal would mark a retreat from public markets for the once notable biotech, which was forced to cut staff last year to save cash after trial setbacks.

    By Feb. 26, 2024
  • FTC
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    Carol Highsmith. (2005). "Apex Bldg." [Photo]. Retrieved from Wikimedia Commons.
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    AbbVie’s Cerevel deal hits an uncommon roadblock

    A “second request” from the Federal Trade Commission could protract the timing of AbbVie’s proposed acquisition, which is slated to close around the middle of the year.

    By Feb. 20, 2024
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    Dilok Klaisataporn
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    BioAge raises $170M to back Phase 2-ready obesity drug

    BioAge’s Series D will fund a study combining its medicine with Eli Lilly’s Zepbound, a strategy the company hopes could help people lose weight while maintaining muscle mass.

    By Feb. 13, 2024
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    Justin Sullivan via Getty Images
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    Gilead to buy CymaBay in $4.3B deal for liver disease drug

    The proposed acquisition is a bet on CymaBay’s drug seladelpar, which is now under FDA review in a chronic liver disease called primary biliary cholangitis.

    By Feb. 12, 2024
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    Maximusnd via Getty Images
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    BridgeBio sells partial rights to dwarfism drug for $100M

    The deal hands Kyowa Kirin rights in Japan to the drug, which is emerging as a potential rival to BioMarin’s marketed medicine Voxzogo.

    By Feb. 7, 2024
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    Christopher Furlong via Getty Images
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    AstraZeneca to invest $300M in US cell therapy plant

    The UK drugmaker is adding a facility in Rockville, Maryland, after a spate of dealmaking in the therapeutic field.

    By Kristin Jensen • Feb. 7, 2024